After being released from prison to embark on a suicide mission, MacGruber must round up his crack team of Vicki St. Elmo and Dixon Piper to take down The Night Stalkers; an organization of international killers led by MacGruber's former boss, Brigadier Commander Enis Queeth. Will the ruthless Queeth destroy America with Plague X... the world’s deadliest biological weapon? Time will tell, my friends. Time will tell.